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Matthias Boll Profile Page
Matthias Boll


Lab: Prof. Dr. Matthias Boll
Department: Institute of Biology/Microbiology
Address: University of Freiburg
Schänzlestr. 1
79104 Freiburg
Phone: +49 761 203 2649
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:
PhD positions available: YES
Research Area: Protein Structure and Function
Research Interests: Enzymes and metabolites involved in the degradation of aromatic pollutants in anaerobic bacteria.


Education & Training: 1986-1992 Diploma in Biology at Albert-Ludwigs-University Freiburg
1993-1996 Dr. rer. nat. in Biology at Albert-Ludwigs-University Freiburg
1998-2002 Habilitation in Microbiology at Albert-Ludwigs-University Freiburg
Employment & Experience: 1997-1998 Post Doc John Innes Centre, Norwich, UK
1998-2004 Associate Professor, University of Freiburg
2004-2006 Assistent Professor (Hochschuldozent), University of Freiburg
2006-2012 Full Professor of Biochemistry, Institute of Biochemistry, University Leipzig
Scientific Activities: 1999-2005 Member of the DFG Priority programme SPP 1070
1999-2005 Member of the DFG Priority programme SPP 1071
Since 2008 Coordinator DFG Priority programme SPP 1319 (BO 1565 9-1/9-2/10-1/10-2 12/2)
Since 2010 Member of the EU collaborative Project MAGIC-PAH (1 PhD funded)
Since 2011 Member of the DFG Research Unit FOR 1570 (BO 1565 11/1)


Honors and Awards:

1996    Hans-Grisebach-Award
1996    VAAM-PhD thesis-Award (Association of German applied and general microbiologists)
1997    Fellowship of the DFG
1998    Fellowship of EU


Selected Publications:

Fuchs G., Boll M. and Heider J. (2011) Microbial degradation of aromatic compounds - from one strategy to four, Nat Rev Microbiol 9, 803-16.Abstract

Kuntze K., Kiefer, P., Baumann S., Seifert, J., von Bergen, M., Vorholt, J.A. and Boll M. (2011) Enzymes involved in the anaerobic degradation of meta-substituted halobenzoates, Mol Microbiol 82, 758-69. Abstract

Kung, J.W., Baumann, S., von Bergen, M., Müller, M., Hagedoorn, P.-L., Hagen, W.R. and Boll, M. (2010) Reversible biological Birch reduction at an extremely low redox potential, J Am Chem Soc, 132, 9850-9856. Abstract

Kung J.W., Löffler C., Dörner K., Heintz D., Gallien S., van Dorsselaer A., Friedrich T. and Boll M. (2009) Identification and characterization of the tungsten-containing class of benzoyl-coenzyme A reductases., Proc Natl Acad Sci 106, 17687-92. Abstract

Heintz D., Gallien S., Wischgoll S., Ullmann A.K., Schaeffer C., Kretzschmar A.K., van Dorsselaer A. and Boll M. (2009) Differential membrane proteome analysis reveals novel proteins involved in the degradation of aromatic compounds in Geobacter metallireducens.  Mol Cell Prot 8, 2159-69. Abstract

Thiele, B., Rieder, O., Jehmlich, N., von Bergen, M., Müller, M. and Boll, M. (2008) Aromatizing cyclohexa-1,5-diene-1-carbonyl-coenzyme a oxidase: characterization and its role in anaerobic aromatic metabolism, J Biol Chem 283, 20713-21. Abstract

Thiele, B., Rieder, O., Golding, B.T., Müller, M. and Boll M. (2008) Mechanism of Enzymatic Birch Reduction: Stereochemical Course and Exchange Reactions of Benzoyl-CoA Reductase, J Am Chem Soc 130, 14050-1. Abstract

Wischgoll, S., Heintz, D., Peters, F., Erxleben, A., Sarnighausen, E., Reski, R., van Dorsselaer, A. and Boll, M. (2005) Gene clusters involved in anaerobic benzoate degradation of Geobacter metallireducens, Mol. Microbiol. 58, 1238-1252. Abstract

Unciuleac, M., Warkentin, E., Boll, M. & Ermler, U. (2004) Crystal structure of 4-hydroxybenzoyl-CoA reductase from Thauera aromatica at 1.6 Å. Inverted electron flow in a xanthine oxidase-type enzyme, Structure, 12, 2249-2256. Abstract

Unciuleac, M. and Boll, M. (2001) Mechanism of ATP-driven electron transfer catalyzed by the benzene ring-reducing enzyme benzoyl-CoA reductase, Proc. Natl. Acad. Sci. 98, 13619-13625. Abstract

SGBM PhD students

SGBM PhD students:

Lena Appel (since February 2020)



Michael Agne (January 2016-April 2022)

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