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Annegret Wilde Profile Page
Annegret Wilde


Lab: Prof. Dr. Annegret Wilde
Department: Molecular Genetics of Prokaryotes
Institute of Biology III
Faculty of Biology
Address: Schänzlestr. 1
79104 Freiburg
Phone: +49 761 203 97828
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:
PhD positions available: YES
Research Area: Molecular Plant Sciences
Research Interests: - Investigations on phototaxis using different photoreceptors
- Elucidating the potential of cyanobacteria as producers of amino acids, proteins as well as biofuels
- Investigations on the role of RNA-based regulators in bacteria
- Characterisation of photosynthetic functions, light-harvesting and its regulation
- Studies on the circadian clock of cyanobacteria


Education & Training: 2006: Humboldt-University Berlin, Germany (Habilitation in Molecular Biology)
1991 - 1994: Humboldt-University Berlin, Germany, (PhD thesis in Genetics)
1985 - 1990: University St. Petersburg, Russia (diploma thesis in Microbiology)
Employment & Experience: Since 2012: W3-Professor, Molecular Genetics, University of Freiburg
2008 - 2012: W2-Professor for Molecular Microbiology, Justus-Liebig University Giessen
2001 - 2008: Senior scientist (C1), Plant Biochemistry, Humboldt-University Berlin
1998 - 2000: Fellowship, Genetics, Humboldt-University Berlin
1994 - 1997: Postdoctoral Fellow, Genetics, Humboldt-University Berlin
1990 - 1991: Scientist, Technical Microbiology, AdW Berlin-Buch
Scientific Activities: 2008 - 2014: Editor of Microbiology
2013 - 2016: Co-Coordinator BMBF-collaborative project e:bio “Systems Biology of Cyanobacterial Biofuel Production”
2014 - 2017: Coordinator of a collaborative project Bioeconomy Baden-Württemberg
Since 2007: Scientific consultant of Algenol Biofuels Germany GmbH
Since 2014: DFG Liaison Officer of the University of Freiburg


Selected Publications:

Han Y, Jakob A, Engel S, Wilde A, Schuergers N. PATAN-domain regulators interact with the Type IV pilus motor to control phototactic orientation in the cyanobacterium Synechocystis. Mol Microbiol. 2021 Dec 22.  Abstract

Hoffmann UA, Heyl F, Rogh SN, Wallner T, Backofen R, Hess WR, Steglich C, Wilde A. Transcriptome-wide in vivo mapping of cleavage sites for the compact cyanobacterial ribonuclease E reveals insights into its function and substrate recognition. Nucleic Acids Res. 2021 Dec 16;49(22):13075-13091.  Abstract

Scheurer NM, Rajarathinam Y, Timm S, Köbler C, Kopka J, Hagemann M, Wilde A. Homologs of Circadian Clock Proteins Impact the Metabolic Switch Between Light and Dark Growth in the Cyanobacterium Synechocystis sp. PCC 6803. Front Plant Sci. 2021 Jun 22;12:675227.  Abstract

Oeser S, Wallner T, Schuergers N, Bučinská L, Sivabalasarma S, Bähre H, Albers SV, Wilde A. Minor pilins are involved in motility and natural competence in the cyanobacterium Synechocystis sp. PCC 6803. Mol Microbiol. 2021 Sep;116(3):743-765.  Abstract

Mahbub M, Hemm L, Yang Y, Kaur R, Carmen H, Engl C, Huokko T, Riediger M, Watanabe S, Liu LN, Wilde A, Hess WR, Mullineaux CW. mRNA localization, reaction centre biogenesis and thylakoid membrane targeting in cyanobacteria. Nat Plants. 2020 Sep;6(9):1179-1191.  Abstract

Köbler C, Schultz SJ, Kopp D, Voigt K, Wilde A. The role of the Synechocystis sp. PCC 6803 homolog of the circadian clock output regulator RpaA in day-night transitions. Mol Microbiol. 2018 Dec;110(5):847-861.  Abstract

Yang Y, Lam V, Adomako M, Simkovsky R, Jakob A, Rockwell NC, Cohen SE, Taton A, Wang J, Lagarias JC, Wilde A, Nobles DR, Brand JJ, Golden SS. Phototaxis in a wild isolate of the cyanobacterium Synechococcus elongatus. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12378-E12387.  Abstract

Behler J, Sharma K, Reimann V, Wilde A, Urlaub H, Hess WR. The host-encoded RNase E endonuclease as the crRNA maturation enzyme in a CRISPR-Cas subtype III-Bv system. Nat Microbiol. 2018 Mar;3(3):367-377.  Abstract

Schuergers N, Lenn T, Kampmann R, Meissner MV, Esteves T, Temerinac-Ott M, Korvink JG, Lowe AR, Mullineaux CW, Wilde A. Cyanobacteria use micro-optics to sense light direction. Elife. 2016 Feb 9;5:e12620.  Abstract

Georg J, Dienst D, Schürgers N, Wallner T, Kopp D, Stazic D, Kuchmina E, Klähn S, Lokstein H, Hess WR, Wilde A. The small regulatory RNA SyR1/PsrR1 controls photosynthetic functions in cyanobacteria. Plant Cell. 2014 Sep;26(9):3661-79.  Abstract

SGBM PhD students

SGBM PhD students:

Jonas Hammerl (since September 2022)



Nibedita Priyadarshini (January 2018-June 2022)

Annik Jakob (January 2016-August 2020)

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