Simon Lagies

Simon Lagies Profile Page

Contact

PhD Lab:	Bernd Kammerer
Department:	Center for Biological Systems Analysis (ZBSA) Core Facility Metabolomics University of Freiburg
Address:	Habsburgerstr. 49 79104 Freiburg
Phone:	+49 (0)761 203 97133
E-mail:	This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:	www.zbsa.uni-freiburg.de/core_fac/Metabolomics
Research Area:	Molecular Medicine

Curriculum Vitae

Country:	Germany
Education/Training:	Bachelor of Science in Molecular Medicine (graduated 2014) Master of Science in Molecular Medicine (graduated 2016)
Start of PhD Thesis:	January 2017
Research Interests:	Metabolomics, energy metabolism, mTOR signaling, kidney diseases, separation techniques
Research Techniques:	Metabolomics, metabolite extraction, gas chromatography, liquid chromatography, ion-mobility spectrometry, mass spectrometry

Publications

Publications:

Liang W, Yamahara K, Hernando-Erhard C, Lagies S, Wanner N, Liang H, Schell C, Kammerer B, Huber TB, Bork T. A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier. Kidney Int. (2020) S0085-2538(20)30715-8. Abstract

Braun LM*, Lagies S*, Klar RFU, Hussung S, Fritsch RM, Kammerer B, Wittel UA. Metabolic Profiling of Early and Late Recurrent Pancreatic Ductal Adenocarcinoma Using Patient-Derived Organoid Cultures. Cancers (2020) 12, 1440. Abstract

Braun LM*, Lagies S*, Guenzle J, Fichtner-Feigl S, Wittel UA, Kammerer B. Metabolic Adaptation during nab-Paclitaxel Resistance in Pancreatic Cancer Cell Lines. Cells (2020) 9, 1251. (*shared first-authorship) Abstract

Lagies S, Schlimpert M, Neumann S, Wäldin A, Kammerer B, Borner C & Peintner L. Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells. Commun Biol (2020) 3, 246. Abstract

Lagies S, Pichler R, Bork T, Kaminski MM, Troendle K, Zimmermann S, Huber TB, Walz G, Lienkamp SS, Kammerer B. Impact of Diabetic Stress Conditions on Renal Cell Metabolome. Cells (2019) 8(10). Abstract

Brinkkoetter PT, Bork T, Salou S, Liang W, Mizi A, Özel C, Koehler S, Hagmann HH, Ising C, Kuczkowski A, Schnyder S, Abed A, Schermer B, Benzing T, Kretz O, Puelles VG, Lagies S, Schlimpert M, Kammerer B, Handschin C, Schell C, Huber TB. Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics. Cell Rep. (2019) 27(5):1551-1566. Abstract

Schlimpert M, Lagies S, Müller B, Budnyk V, Blanz KD, Walz G, Kammerer B. Metabolic perturbations caused by depletion of nephronophthisis factor Anks6 in mIMCD3 cells. Metabolomics. (2019) 15(5):71. Abstract

Lagies S, Schlimpert M, Braun LM, Kather M, Plagge J, Erbes T, Wittel UA, Kammerer B. Unraveling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry. Anal Bioanal Chem. (2019) doi: 10.1007/s00216-019-01814-1. Abstract

Schlimpert M, Lagies S, Budnyk V, Müller B, Walz G, Kammerer B. Metabolic Phenotyping of Anks3 Depletion in mIMCD-3 cells - a Putative Nephronophthisis Candidate. Sci Rep. (2018) 8(1):9022. Abstract

Pan D, Lindau C, Lagies S, Wiedemann N, Kammerer B. Metabolic profiling of isolated mitochondria and cytoplasm reveals compartment-specific metabolic responses. Metabolomics. (2018) 14(5):59. Abstract

Lagies S, Pichler R, Kaminski MM, Schlimpert M, Walz G, Lienkamp SS, Kammerer B. Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs). Sci Rep. (2018) 8(1):3878. Abstract