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Andreas Vlachos Profile Page
Andreas Vlachos


Lab: Prof. Dr. Andreas Vlachos
Department: Institute for Anatomy and Cell Biology
Dept. Neuroanatomy
Address: Albertstr. 17
79104 Freiburg
Phone: +49 (0)761 203 5056
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:
PhD positions available: YES
Research Area: Neurosciences
Research Interests: - Structural and functional plasticity of neurons and their molecular regulation.
- Role of homeostatic plasticity at the interface between health and disease.
- Cellular and molecular mechanisms of transcranial magnetic stimulation (TMS).
- Impact of neuroinflammation and neurocoagulation on neuro-glial interactions and synaptic plasticity.


Education & Training: 2001-2008: Medical studies, Goethe-University Frankfurt
08/2008: Licensed doctor, Goethe-University Frankfurt
02/2010: MD thesis, Goethe-University Frankfurt
06/2014: Habilitation, Goethe-University Frankfurt
Employment & Experience: Since May 2017: Full Professor, Head of Department, Institute of Anatomy and Cell Biology, Department of Neuroanatomy, Albert-Ludwigs-University of Freiburg
03/2016-04/2017: Associate Professor, Institute of Anatomy II, Heinrich-Heine University, Düsseldorf
2010-2016: Group leader, Institute of Clinical Neuroanatomy, Goethe-University Frankfurt
2008-2010: Assistant, Institute of Clinical Neuroanatomy, Goethe-University Frankfurt
2006: Visiting researcher in the group of Menahem Segal, Department of Neurobiology, Weizmann institute of Science, Rehovot


Honors and Awards:

2003: Scholarship Award, Studienstiftung des Deutschen Volkes
2010: Thesis award - Promotionspreis der Hessischen Landesärztekammer
2011: Bargmann-Award of Anatomische Gesellschaft
2012: Junior Researcher in Focus Program of Goethe-University Frankfurt
2013:  Award for Excellent Teaching – Faculty of Medicine, Goethe-University Frankfurt
2014: Young Investigator Award of Anatomische Gesellschaft (109th Annual meeting),
2017: Award for Excellent Teaching – Faculty of Medicine, Heinrich-Heine-University, Düsseldorf


Selected Publications:

Shavit-Stein E, Artan-Furman A, Feingold E, Ben Shimon M, Itzekson-Hayosh Z, Chapman J, Vlachos A, Maggio N. Protease Activated Receptor 2 (PAR2) Induces Long-Term Depression in the Hippocampus through Transient Receptor Potential Vanilloid 4 (TRPV4). Front Mol Neurosci. 2017 Mar 2;10:42.  Abstract

Lenz M, Galanis C, Müller-Dahlhaus F, Opitz A, Wierenga CJ, Szabó G, Ziemann U, Deller T, Funke K, Vlachos A. Repetitive magnetic stimulation induces plasticity of inhibitory synapses. Nat Commun. 2016 Jan 8;7:10020.  Abstract

Liu X, Huai J, Endle H, Schlüter L, Fan W, Li Y, Richers S, Yurugi H, Rajalingam K, Ji H, Cheng H, Rister B, Horta G, Baumgart J, Berger H, Laube G, Schmitt U, Schmeisser MJ, Boeckers TM, Tenzer S, Vlachos A, Deller T, Nitsch R, Vogt J. PRG-1 Regulates Synaptic Plasticity via Intracellular PP2A/β1-Integrin Signaling. Dev Cell. 2016 Aug 8;38(3):275-90.  Abstract

Lenz M, Platschek S, Priesemann V, Becker D, Willems LM, Ziemann U, Deller T, Müller-Dahlhaus F, Jedlicka P, Vlachos A. Repetitive magnetic stimulation induces plasticity of excitatory postsynapses on proximal dendrites of cultured mouse CA1 pyramidal neurons. Brain Struct Funct. 2015 Nov;220(6):3323-37.  Abstract

Vlachos A, Ikenberg B, Lenz M, Becker D, Reifenberg K, Bas-Orth C, Deller T. Synaptopodin regulates denervation-induced homeostatic synaptic plasticity. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8242-7.  Abstract

Vlachos A, Helias M, Becker D, Diesmann M, Deller T. NMDA-receptor inhibition increases spine stability of denervated mouse dentate granule cells and accelerates spine density recovery following entorhinal denervation in vitro. Neurobiol Dis. 2013 Nov;59:267-76.  Abstract

Vlachos A, Reddy-Alla S, Papadopoulos T, Deller T, Betz H. Homeostatic regulation of gephyrin scaffolds and synaptic strength at mature hippocampal GABAergic postsynapses. Cereb Cortex. 2013 Nov;23(11):2700-11.  Abstract

Vlachos A, Müller-Dahlhaus F, Rosskopp J, Lenz M, Ziemann U, Deller T. Repetitive magnetic stimulation induces functional and structural plasticity of excitatory postsynapses in mouse organotypic hippocampal slice cultures. J Neurosci. 2012 Nov 28;32(48):17514-23.  Abstract

Vlachos A, Korkotian E, Schonfeld E, Copanaki E, Deller T, Segal M. Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons. J Neurosci. 2009 Jan 28;29(4):1017-33.  Abstract

Zolles G, Wenzel D, Bildl W, Schulte U, Hofmann A, Müller CS, Thumfart JO, Vlachos A, Deller T, Pfeifer A, Fleischmann BK, Roeper J, Fakler B, Klöcker N. Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels to cAMP and adrenergic stimulation. Neuron. 2009 Jun 25;62(6):814-25.  Abstract

SGBM PhD students

SGBM PhD students:



Dimitrios Kleidonas (August 2018-December 2022)

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