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Peter Walentek Profile Page
Peter Walentek

Contact

Lab: Dr. Peter Walentek
Department: Internal Medicine IV, University Medical Center
and ZBSA, Center for Systems Biological Analysis
Phone: +49 761 203 97206
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage: www.uniklinik-freiburg.de/walentek-en.html
PhD positions available: YES
Research Area: Developmental Biology
Research Interests: We study the molecular mechanisms of mucociliary development, regeneration and disease. Mucociliary epithelia provide an important first line of defense against pathogens for the organism. We are particularly interested to elucidate the interactions between cell signaling, transcriptional and post-transcriptional regulation of gene regulatory networks, and the morphogenetic processes at the cellular and tissue-wide levels, which facilitate complex tissue formation and function. Our work aims to provide crucial insights into the logic of self-organization in biological systems as well as into the molecular mechanisms underlying ciliopathies and chronic lung diseases.

CV

Education & Training: 09/2012: Dr. rer. nat., Developmental & Molecular Biology, University of Hohenheim, Stuttgart, Germany
11/2007: Diplom Biologie, Zoology, Animal Ecology & Membrane Physiology, University of Hohenheim, Stuttgart, Germany

Employment & Experience: 2016-2017: K99 Principal Investigator, Translational & Developmental Biology, Department of Cell and Molecular Biology, and Center for Integrative Genomics, UC Berkeley, CA, USA
2012-2015: Postdoctoral Fellow, Cell & Developmental Biology, Department of Cell and Molecular Biology, and Center for Integrative Genomics, UC Berkeley, CA, USA
2008-2012: PhD Student, Developmental and Molecular Biology, University of Hohenheim, Stuttgart, Germany
2006: Undergraduate Researcher, Regenerative and Developmental Biology, Forsyth Institute, Harvard University, Boston, and Marine Biology Laboratory, Woods Hole, MA, USA

Honors

Honors and Awards:

2017: Emmy Noether Research Group - Deutsche Forschungsgemeinschaft (DFG).
2016: Pathway to Independence Award (K99/R00) - NIH, National Heart, Lung, and Blood Institute (NIH).
2015: Outstanding Postdoctoral Fellow Award - Molecular and Cell Biology Department, UC Berkeley.
2015: Hilde Mangold Postdoctoral Award: Society for Developmental Biology best postdoctoral presentation award at Hilde Mangold Symposium, 74th SDB Meeting, Snowbird, UT / USA.
2015: Best postdoctoral presentation award - West Coast Meeting of the Society for Developmental
Biology, Tenaya Lodge at Yosemite, USA.
2013: PhD thesis award - Wissenschaftspreis des Universitätbundes Hohenheim.
2013: Best presentation award - 32nd West Coast Salt and Water Club Meeting, Morrow Bay, USA.
2012-2014: Postdoctoral Fellowship - Deutsche Forschungsgemeinschaft (DFG).
2009-2011: PhD Fellowship - Landesgraduiertenförderung Baden-Württemberg (LGFG).
2006: Undergraduate Fellowship - Herzog-Carl-Stipendium.

Publications

Selected Publications:

Walentek P*, Boutin C*, Kodjabachian L* (2017). Planar cell polarity in ciliated cells and epithelia. Book chapter for Cell Polarity in Development and Disease.

Walentek P, Quigley IK. What we can learn from a tadpole about ciliopathies and airway diseases: Using systems biology in Xenopus to study cilia and mucociliary epithelia. Genesis. 2017 Jan;55(1-2).  Abstract

Walentek P, Quigley IK, Sun DI, Sajjan UK, Kintner C, Harland RM. Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis. Elife. 2016 Sep 13;5.  Abstract

Walentek P, Beyer T, Hagenlocher C, Müller C, Feistel K, Schweickert A, Harland RM, Blum M. ATP4a is required for development and function of the Xenopus mucociliary epidermis - a potential model to study proton pump inhibitor-associated pneumonia. Dev Biol. 2015 Dec 15;408(2):292-304.  Abstract

Dichmann DS, Walentek P, Harland RM. The alternative splicing regulator Tra2b is required for somitogenesis and regulates splicing of an inhibitory Wnt11b isoform. Cell Rep. 2015 Feb 3;10(4):527-36.  Abstract

Walentek P, Song R, He L. microRNAs and cilia. An ancient connection. Cell Cycle. 2014;13(15):2315-6.  Abstract

Song R, Walentek P, Sponer N, Klimke A, Lee JS, Dixon G, Harland R, Wan Y, Lishko P, Lize M, Kessel M, He L. miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110. Nature. 2014 Jun 5;510(7503):115-20.  Abstract

Walentek P, Bogusch S, Thumberger T, Vick P, Dubaissi E, Beyer T, Blum M, Schweickert A. A novel serotonin-secreting cell type regulates ciliary motility in the mucociliary epidermis of Xenopus tadpoles. Development. 2014 Apr;141(7):1526-33.  Abstract

Walentek P, Schneider I, Schweickert A, Blum M. Wnt11b is involved in cilia-mediated symmetry breakage during Xenopus left-right development. PLoS One. 2013 Sep 13;8(9):e73646.  Abstract

Walentek P, Beyer T, Thumberger T, Schweickert A, Blum M. ATP4a is required for Wnt-dependent Foxj1 expression and leftward flow in Xenopus left-right development. Cell Rep. 2012 May 31;1(5):516-27.  Abstract

SGBM PhD students

SGBM PhD students:

Track 2:

Maximilian Haas (since March 2018)

 

CIBSS Track:

Magdalena Brislinger (since October 2018)

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