Peter Kohl

Peter Kohl Profile Page

Contact

Lab:	Prof. Dr. Peter Kohl
Department:	Institute for Experimental Cardiovascular Medicine University of Freiburg
Address:	Elsässer Str. 2Q 79110 Freiburg
Phone:	+49 761 270 63950
E-mail:	This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:	www.herzzentrum.de/englisch/departments-sections/institute-for-experimental-cardiovascular-medicine.html
PhD positions available:	YES
Research Area:	Molecular Medicine

CV

Employment & Experience:

1987-1992: PhD Student / Research Scientist, Charité Hospital, Humboldt University Berlin, Germany
1992-1997: Post-doctoral Scientist with Prof D. Noble, University Laboratory of Physiology, University of Oxford, UK
1997-2000: Research Fellow, University Laboratory of Physiology, University of Oxford, UK
2000-2004: University Research Lecturer, University Laboratory of Physiology, University of Oxford, UK
2002-2004: Research Fellow, Keble College, Oxford, UK
2004-2010: Reader in Cardiac Physiology, Physiology, Anatomy and Genetics, University of Oxford, UK
2004-2010: Tutorial Fellow, Balliol College, Oxford, UK
2010-2017: Professor, Chair in Cardiac Biophysics and Systems Biology, Imperial College London, UK
2010-2017: Deputy Director for Research, Magdi Yacoub Institute, Harefield, UK
Since 2015: Director, Institute for Experimental Cardiovascular Medicine, University of Freiburg, Germany
Since 2015: Scientific Director, University Heart Centre Freiburg / Bad Krozingen, Germany
Since 2020: Speaker of the Collaborative Research Centre SFB1425 ”Make better Scars!”

Honors

Honors and Awards:

1996: Honorary MA, University of Oxford
1997-2005: Royal Society Research Fellow, UK
2005-2017: Senior Fellow of the British Heart Foundation, UK
2006-2009: College of Experts, Medical Research Council, UK
Since 2010: Visiting Professor, University of Oxford, UK
Since 2011: Fellow of the Heart Rhythm Society, USA
2011-2016: Japanese National High Performance Computing Initiative, Chair of the Advisory Board
2013-2016: Joint Research Center for Computational Biomedicine of RWTH Aachen and Bayer, Advisory Board
2013: Winner of a European Research Council Advanced Grant Award
Since 2014: Fellow of the American Heart Association
2015: Chair of Cardiac Arrhythmias Gordon Research Conference
2015: Chair of Keystone Symposium: Beyond the Myocyte-Centric View of the Heart
Since 2022: Editor in Chief, The Journal of Physiology, London

Publications

Selected Publications:

Quinn TA, Kohl P. Cardiac Mechano-Electric Coupling: Acute Effects of Mechanical Stimulation on Heart Rate and Rhythm. Physiol Rev. 2021 Jan 1;101(1):37-92. Abstract

Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska EA, Peyronnet R, Seyfferth J, Chen HR, de Leeuw R, Herquel B, Kimura H, Mittler G, Kohl P, Medalia O, Korbel JO, Akhtar A. The NSL complex maintains nuclear architecture stability via lamin A/C acetylation. Nat Cell Biol. 2019 Oct;21(10):1248-1260. Abstract

Chen J, Arentz T, Cochet H, Müller-Edenborn B, Kim S, Moreno-Weidmann Z, Minners J, Kohl P, Lehrmann H, Allgeier J, Trenk D, Hocini M, Jais P, Haissaguerre M, Jadidi A. Extent and spatial distribution of left atrial arrhythmogenic sites, late gadolinium enhancement at magnetic resonance imaging, and low-voltage areas in patients with persistent atrial fibrillation: comparison of imaging vs. electrical parameters of fibrosis and arrhythmogenesis. Europace. 2019 Oct 1;21(10):1484-1493. Abstract

Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S, Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA. Primary cilia defects causing mitral valve prolapse. Sci Transl Med. 2019 May 22;11(493):eaax0290. Abstract

Bernal Sierra YA, Rost BR, Pofahl M, Fernandes AM, Kopton RA, Moser S, Holtkamp D, Masala N, Beed P, Tukker JJ, Oldani S, Bönigk W, Kohl P, Baier H, Schneider-Warme F, Hegemann P, Beck H, Seifert R, Schmitz D. Potassium channel-based optogenetic silencing. Nat Commun. 2018 Nov 5;9(1):4611. Abstract

Kong CHT, Rog-Zielinska EA, Kohl P, Orchard CH, Cannell MB. Solute movement in the t-tubule system of rabbit and mouse cardiomyocytes. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7073-E7080. Abstract

Weber M, Scherf N, Meyer AM, Panáková D, Kohl P, Huisken J. Cell-accurate optical mapping across the entire developing heart. Elife. 2017 Dec 29;6. Abstract

Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Sloan CL, Pereira RO, Lira VA, Spitzer KW, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED. Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission. Circ Res. 2018 Jan 5;122(1):58-73. Abstract

Quinn TA, Jin H, Lee P, Kohl P. Mechanically Induced Ectopy via Stretch-Activated Cation-Nonselective Channels Is Caused by Local Tissue Deformation and Results in Ventricular Fibrillation if Triggered on the Repolarization Wave Edge (Commotio Cordis). Circ Arrhythm Electrophysiol. 2017 Aug;10(8). Abstract

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L. Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy. Proc Natl Acad Sci U S A. 2017 May 30;114(22):5737-5742. Abstract

SGBM PhD students

SGBM PhD students:

Bo Han (since October 2020)

Alumni:

Elisa Darkow (October 2019-July 2022)