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Peter Kohl Profile Page
Peter Kohl

Contact

Lab: Prof. Dr. Peter Kohl
Department: Institute for Experimental Cardiovascular Medicine
University of Freiburg
Address: Elsässer Str. 2Q
79110 Freiburg
Phone: +49 761 270 63950
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage: www.herzzentrum.de/englisch/departments-sections/institute-for-experimental-cardiovascular-medicine.html
PhD positions available: YES
Research Area: Molecular Medicine

CV

Employment & Experience: 1987-1992: PhD Student / Research Scientist, Charité Hospital, Humboldt University Berlin, Germany
1992-1997: Post-doctoral Scientist with Prof D. Noble, University Laboratory of Physiology, University of Oxford, UK
1997-2000: Research Fellow, University Laboratory of Physiology, University of Oxford, UK
2000-2004: University Research Lecturer, University Laboratory of Physiology, University of Oxford, UK
2002-2004: Research Fellow, Keble College, Oxford, UK
2004-2010: Reader in Cardiac Physiology, Physiology, Anatomy and Genetics, University of Oxford, UK
2004-2010: Tutorial Fellow, Balliol College, Oxford, UK
2010-2017: Professor, Chair in Cardiac Biophysics and Systems Biology, Imperial College London, UK
2010-2017: Deputy Director for Research, Magdi Yacoub Institute, Harefield, UK
Since 2015: Director, Institute for Experimental Cardiovascular Medicine, University of Freiburg, Germany
Since 2015: Scientific Director, University Heart Centre Freiburg / Bad Krozingen, Germany

Honors

Honors and Awards:

1996: Honorary MA, University of Oxford
1997-2005: Royal Society Research Fellow, UK
2005-2017: Senior Fellow of the British Heart Foundation, UK
2006-2009: College of Experts, Medical Research Council, UK
Since 2010: Visiting Professor, University of Oxford, UK
Since 2011: Fellow of the Heart Rhythm Society, USA
2011-2016: Japanese National High Performance Computing Initiative, Chair of the Advisory Board
2013-2016: Joint Research Center for Computational Biomedicine of RWTH Aachen and Bayer, Advisory Board
2013: Winner of a European Research Council Advanced Grant Award
Since 2014: Fellow of the American Heart Association
2015: Chair of Cardiac Arrhythmias Gordon Research Conference
2015: Chair of Keystone Symposium: Beyond the Myocyte-Centric View of the Heart

Publications

Selected Publications:

Bernal Sierra YA, Rost BR, Pofahl M, Fernandes AM, Kopton RA, Moser S, Holtkamp D, Masala N, Beed P, Tukker JJ, Oldani S, Bönigk W, Kohl P, Baier H, Schneider-Warme F, Hegemann P, Beck H, Seifert R, Schmitz D. Potassium channel-based optogenetic silencing. Nat Commun. 2018 Nov 5;9(1):4611.  Abstract

Kong CHT, Rog-Zielinska EA, Kohl P, Orchard CH, Cannell MB. Solute movement in the t-tubule system of rabbit and mouse cardiomyocytes. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7073-E7080.  Abstract

Weber M, Scherf N, Meyer AM, Panáková D, Kohl P, Huisken J. Cell-accurate optical mapping across the entire developing heart. Elife. 2017 Dec 29;6.  Abstract

Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Sloan CL, Pereira RO, Lira VA, Spitzer KW, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED. Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission. Circ Res. 2018 Jan 5;122(1):58-73.  Abstract

Quinn TA, Jin H, Lee P, Kohl P. Mechanically Induced Ectopy via Stretch-Activated Cation-Nonselective Channels Is Caused by Local Tissue Deformation and Results in Ventricular Fibrillation if Triggered on the Repolarization Wave Edge (Commotio Cordis). Circ Arrhythm Electrophysiol. 2017 Aug;10(8).  Abstract

Scardigli M, Crocini C, Ferrantini C, Gabbrielli T, Silvestri L, Coppini R, Tesi C, Rog-Zielinska EA, Kohl P, Cerbai E, Poggesi C, Pavone FS, Sacconi L. Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy. Proc Natl Acad Sci U S A. 2017 May 30;114(22):5737-5742.  Abstract

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017 Apr 20;169(3):510-522.e20.  Abstract

Decher N, Ortiz-Bonnin B, Friedrich C, Schewe M, Kiper AK, Rinné S, Seemann G, Peyronnet R, Zumhagen S, Bustos D, Kockskämper J, Kohl P, Just S, González W, Baukrowitz T, Stallmeyer B, Schulze-Bahr E. Sodium permeable and "hypersensitive" TREK-1 channels cause ventricular tachycardia. EMBO Mol Med. 2017 Apr;9(4):403-414.  Abstract

Quinn TA, Camelliti P, Rog-Zielinska EA, Siedlecka U, Poggioli T, O'Toole ET, Knöpfel T, Kohl P. Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14852-14857.  Abstract

Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Rog-Zielinska EA, Hebisch E, Dura M, Didié M, Gotthardt M, Nikolaev VO, Hasenfuss G, Kohl P, Ward CW, Lederer WJ, Lehnart SE. Axial tubule junctions control rapid calcium signaling in atria. J Clin Invest. 2016 Oct 3;126(10):3999-4015.  Abstract

SGBM PhD students

SGBM PhD students:

Elisa Darkow (since October 2019)

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