Ralf Baumeister

Ralf Baumeister Profile Page

Contact

Lab:	Prof. Dr. Ralf Baumeister
Department:	Bioinformatics and Molecular Biology (Bio3, Faculty of Biology) Center for Biochemistry and Molecular Cell Research (ZBMZ, Faculty of Medicine)
Address:	Schänzlestr. 1 D-79104 Freiburg
Phone:	+49 (761) 203 8350
E-mail:	This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:	celegans.biologie.uni-freiburg.de
PhD positions available:	YES
Research Area:	Molecular Medicine
Research Interests:	Molecular genetics and biochemistry of aging and age-related diseases, tumor, longevity, stress biology, signaling mechanisms.

CV

Education & Training:	1982-1987 Diploma in Biology, University of Erlangen/Nürnberg 1987-1992 PhD in Microbiology, University of Erlangen-Nürnberg 2001 Habilitation in Biochemistry, LMU Munich, (Prof. Dr. E. Winnacker)
Employment & Experience:	since 2006 W3 Professor (Ordinarius), Faculties of Biology and Medicine 2003-2006 C4 Professor (Ordinarius), Bioinformatics and Molecular Genetics, Faculty of Biology, University of Freiburg 2000-2003 C3 Professor (Metabolic Chemistry), Adolf-Butenandt-Inst., Faculty of Medicine, LMU Munich 1995-2000 Group Leader Neurogenetics, Genzentrum LMU Munich 1992-1995 Postdoctorate, Harvard Med. School, Mass. General Hospital, Boston, USA
Scientific Activities:	2010-2012 Internal Senior Fellow FRIAS LIFENET 2007-2010 Director of LIFENET at FRIAS – Freiburg Institute of Advanced Studies 2007-2008 Director of Institute of Biology 3, Faculty of Biology 2005-2010 Director of ZBSA (Zentrum für Biosystemanalyse) Freiburg 1998 Founder of the Biotech Company ELEGENE Inc.

Honors

Honors and Awards:

1988-1990: Stipend, Begabtenförderung des Freistaats Bayern

1988: Eva-Schleip Stipend, Erlangen
1989: EMBO Fellowship, Research Visit at Karolinska Institute, Stockholm
1993: PhD Prize, VAAM e.V (Vereinigung f. Allg. und Angew. Mikrobiologie)

1993-1995: EMBO and DFG (German Research Council) Research fellowships
1995: American Cancer Society Mass. Div., Research fellowship
2001: Philip-Morris Research Prize
2002: Familie-Hansen Research Prize of Bayer AG
2003: Recipient of Qualitätsoffensive Program by the State of Baden-W.

2009: Alzheimer Research Prize 2008 of the Hans and Ilse Breuer Foundation

Publications

Selected Publications:

Baumeister R, Murphy CT, Heimbucher T. Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress? Cell Death Differ. 2021 Apr;28(4):1434-1436. Abstract

Kienle K, Glaser KM, Eickhoff S, Mihlan M, Knöpper K, Reátegui E, Epple MW, Gunzer M, Baumeister R, Tarrant TK, Germain RN, Irimia D, Kastenmüller W, Lämmermann T. Neutrophils self-limit swarming to contain bacterial growth in vivo. Science. 2021 Jun 18;372(6548):eabe7729. Abstract

Qi W, Gromoff EDV, Xu F, Zhao Q, Yang W, Pfeifer D, Maier W, Long L, Baumeister R. The secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans. Nat Commun. 2021 Feb 24;12(1):1262. Abstract

Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium, de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling. Cell. 2021 Feb 4;184(3):655-674.e27. Abstract

Heimbucher T, Qi W, Baumeister R. TORC2-SGK-1 signaling integrates external signals to regulate autophagic turnover of mitochondria via mtROS. Autophagy. 2020 Jun;16(6):1154-1156. Abstract

Aspernig H, Heimbucher T, Qi W, Gangurde D, Curic S, Yan Y, Donner von Gromoff E, Baumeister R, Thien A. Mitochondrial Perturbations Couple mTORC2 to Autophagy in C. elegans. Cell Rep. 2019 Nov 5;29(6):1399-1409.e5. Abstract

Kvainickas A, Nägele H, Qi W, Dokládal L, Jimenez-Orgaz A, Stehl L, Gangurde D, Zhao Q, Hu Z, Dengjel J, De Virgilio C, Baumeister R, Steinberg F. Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid-induced mTORC1 signaling. J Cell Biol. 2019 Sep 2;218(9):3019-3038. Abstract

Qi W, Yan Y, Pfeifer D, Donner V Gromoff E, Wang Y, Maier W, Baumeister R. C. elegans DAF-16/FOXO interacts with TGF-ß/BMP signaling to induce germline tumor formation via mTORC1 activation. PLoS Genet. 2017 May 26;13(5):e1006801. Abstract

Thien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K. TSC1 activates TGF-β-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition. Dev Cell. 2015 Mar 9;32(5):617-30. Abstract

SGBM PhD students

SGBM PhD students:

Fan Xu (since November 2019)

Alumni

Eva Runkel (06/2008 - 07/2013)

Tamara Prentzell (04/2012 - 05/2018)