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Wolfgang Driever Profile Page
Wolfgang Driever


Lab: Prof. Dr. Wolfgang Driever
Department: Department of Biology I
Phone: 203 2587
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:
BIOSS Excellence Cluster: Member
PhD positions available: YES
Research Area: Developmental Biology
Research Interests: Embryonic Development of Vertebrates (Zebrafish)
Development of dopaminergic neurons
Dopaminergic modulation of neural circuit function and behavior


Education & Training: 1979-1986: Study of Biochemistry, Eberhard-Karls University Tübingen, Germany
1989: PhD, summa cum laude, Developmental Biology, Eberhard-Karls University and MPI Developmental Biology, Tübingen, Germany
Employment & Experience: 1989-1990: Postdoctoral research in laboratory of Dr. Christiane Nüsslein-Volhard, Max-Planck-Institute of Developmental Biology, Tübingen
1990-1991: Postdoctoral research in laboratory of Dr. Monte Westerfield, University of Oregon, USA
1991-1996: Assistant Professor of Medicine (Genetics), Harvard Medical School and Massachusetts General Hospital, Boston, USA
1996-present: Full Professor (W3) for Developmental Biology of Animals at the Institute of Biology I, University of Freiburg
1997: Co-Founder, DeveloGen AG, Göttingen, Germany
2001-present: Sprecher, SFB 592 Signalmechanismen in Embryogenese und Organogenese, University of Freiburg
2005-2010: Member, Board of Directors, Zentrum für BioSystemAnalyse ZBSA der Universität Freiburg
Scientific Activities: 1994-2008: Editorial Board, Development
1995-present: Editorial Board, Developmental Biology
1999-present: Editorial Board, Mechanisms of Development and GEP
2004-present: Editorial Advisor, BMC Developmental Biology
1994-present: Member, American Society for Neuroscience
1994-present: Member, American Society for Developmental Biology
1997-present: Member, Deutsche Gesellschaft für Entwicklungsbiologie
1994: Organizer, Cold Spring Harbor Meeting Zebrafish Development and Genetics
2002-2005: Coordinator of Initiative "Zentrum für BioSystemAnalyse / Center for Systems Biology" (ZBSA) Freiburg


Honors and Awards:
1986-1988: Max-Planck scholarship
1988: Otto Hahn Award of the Max-Planck-Society
1997: Otto Mangold Award of the German Society for Developmental Biology
1998-1999: President, German Society for Developmental Biology (GfE)
2008-2012: Internal Fellow, Freiburg Institute of Advanced Studies FRIAS


Selected Publications:

Kubo, F., Hablitzel, B., Maschio, M.D., Driever, W., Baier, H., and Arrenberg, A.B. (2014). Functional Architecture of an Optic Flow-Responsive Area that Drives Horizontal Eye Movements in Zebrafish. Neuron 81, 1344–1359. Abstract

Filippi, A., Mueller, T., and Driever, W. (2014). vglut2 and gad expression reveal distinct patterns of dual GABAergic versus glutamatergic cotransmitter phenotypes of dopaminergic and noradrenergic neurons in the zebrafish brain. J Comp Neurol 522, 2019–2037. Abstract

Leichsenring, M., Maes, J., Mössner, R., Driever, W., and Onichtchouk, D. (2013). Pou5f1 transcription factor controls zygotic gene activation in vertebrates. Science 341, 1005–1009. Abstract

Song, S., Eckerle, S., Onichtchouk, D., Marrs, J.A., Nitschke, R., and Driever, W. (2013). Pou5f1-Dependent EGF Expression Controls E-Cadherin Endocytosis, Cell Adhesion, and Zebrafish Epiboly Movements. Developmental Cell 24, 486–501. Abstract

Schweitzer, J., Löhr, H., Bonkowsky, J.L., Hübscher, K., and Driever, W. (2013). Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development 140, 93–106. Abstract

Ronneberger, O., Liu, K., Rath, M., Rueβ, D., Mueller, T., Skibbe, H., Drayer, B., Schmidt, T., Filippi, A., Nitschke, R., et al. (2012). ViBE-Z: a framework for 3D virtual colocalization analysis in zebrafish larval brains. Nature Methods 9, 735–742. Abstract

Fernandes, A.M., Fero, K., Arrenberg, A.B., Bergeron, S.A., Driever, W., and Burgess, H.A. (2012). Deep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae. Curr Biol 22, 2042–2047. Abstract

Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W (2011) Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nature Communications 2: 171 - DOI: 10.1038/ncomms1171 Abstract

Onichtchouk, D., Geier, F., Polok, B., Messerschmidt, D. M., Mossner, R., Wendik, B., Song, S., Taylor, V., Timmer, J. and Driever, W. (2010). Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development. Mol Syst Biol 6, 354. Abstract

Kastenhuber, E., Kern, U., Bonkowsky, J. L., Chien, C. B., Driever, W. and Schweitzer, J. (2009). Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. J Neurosci 29, 8914-26. Abstract

SGBM PhD students

SGBM PhD students:



Christian Sigloch (11/2014-06/2021)

Pooja Sant (01/2015-02/2021)

Sung Min Song (06/2008 - 02/2013)


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