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Gerd Walz Profile Page
Gerd Walz


Lab: Prof. Dr. Gerd Walz
Department: Department of Medicine, Renal Division
University Medical Center
Phone: 270 32500
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:
BIOSS Excellence Cluster: Member
PhD positions available: YES
Research Area: Molecular Medicine
Research Interests: Pathogenesis of renal cystic disease


Education & Training: 1976-1983: MD, Medicine, Free University, Berlin, Germany
1984: Dr. med., Medicine, Free University, Berlin, Germany
Employment & Experience: 2010-2011 Deputy Chief Executive Director, University Freiburg Medical Center
1999-present Full Professor, Chief, Renal Division, University Freiburg Medical Center
1995-1999 Attending Physician, Assistant Professor of Medicine, Beth Israel Hospital, Harvard Medical School, USA
1994-1995 Renal Fellow and Instructor of Medicine, Brigham and Women’s Hospital, Harvard Medical School, USA
1992-1994 Resident, Deparment of Medicine, Beth Israel Hospital, Harvard Medical School, USA
1987-1992 Research Fellow, Department of Transplant Immunology, Molecular Biology, Harvard Medical School, Boston, USA
1983-1987 Resident, Deparment of Medicine, Free University Berlin
Scientific Activities: 2006-present Academic Consultant of the Nephrology Institute, Changzheng Medical University, Shanghai, China
2002-2004 Panel Member, Welcome Trust, London


Honors and Awards:

2011        Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease
2010        Member, National Academy of Science Germany (Leopoldina)
2008        Ernst-Jung-Prize in Medicine
1991        Special Fellowship, Leukemia Society America, USA
1989        Transplantation Award, ASTP, Chicago

US 5801044 Nucleic acid encoding an antibody that inhibits cell adhesion protein-carbohydrate interactions
US 5723583 Antibody containings sialyl lewis X determinants
EU 06000963.6 Method for diagnosing polycystic kidney disease (pending)


Selected Publications:

Thien A, Prentzell MT, Holzwarth B, et al. TSC1 Activates TGF-beta-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition. Dev Cell 2015; 32(5): 617-30. Abstract

Hoff S, Halbritter J, Epting D, et al. ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet 2013; 45(8): 951-6. Abstract

Lienkamp SS, Liu K, Karner CM, et al. Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. Nat Genet 2012; 44(12): 1382-7. Abstract

Chaki M, Airik R, Ghosh AK, et al. Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell 2012; 150(3): 533-48. Abstract

Lienkamp S, Ganner A, Boehlke C, et al. Inversin relays Frizzled-8 signals to promote proximal pronephros development. Proc Natl Acad Sci U S A 2010; 107(47): 20388-93. Abstract

Boehlke C, Kotsis F, Patel V, et al. Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat Cell Biol 2010; 12(11): 1115-22. Abstract

Walz G, Budde K, Mannaa M, et al. Everolimus in patients with autosomal dominant polycystic kidney disease. N Engl J Med 2010; 363(9): 830-40. Abstract

Ganner A, Lienkamp S, Schafer T, et al. Regulation of ciliary polarity by the APC/C. Proc Natl Acad Sci U S A 2009; 106(42): 17799-804. Abstract

Skouloudaki K, Puetz M, Simons M, et al. Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proc Natl Acad Sci U S A 2009; 106(21): 8579-84. Abstract

Simons M, Gloy J, Ganner A, et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005; 37(5): 537-43. Abstract

SGBM PhD students

SGBM PhD students:

Track 1:
Alexandra Bona (since October 2016)



Track 1:
Yun Hee Kim (03/2009 - 06/2013)

Track 2:
Sylvia Hoff (01/2009 - 09/2013)

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