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Contact
| Lab: | Prof. Dr. Gerd Walz |
| Department: | Department of Medicine, Renal Division University Medical Center |
| Phone: | 270 32500 |
| E-mail: | This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
| Lab homepage: | www.nephrolab.org/groups/gerd-walz/research/ |
| BIOSS Excellence Cluster: | Member |
| PhD positions available: | YES |
| Research Area: | Molecular Medicine |
| Research Interests: | Pathogenesis of renal cystic disease |
CV
| Education & Training: | 1976-1983: MD, Medicine, Free University, Berlin, Germany 1984: Dr. med., Medicine, Free University, Berlin, Germany |
| Employment & Experience: | 2010-2011 Deputy Chief Executive Director, University Freiburg Medical Center 1999-present Full Professor, Chief, Renal Division, University Freiburg Medical Center 1995-1999 Attending Physician, Assistant Professor of Medicine, Beth Israel Hospital, Harvard Medical School, USA 1994-1995 Renal Fellow and Instructor of Medicine, Brigham and Women’s Hospital, Harvard Medical School, USA 1992-1994 Resident, Deparment of Medicine, Beth Israel Hospital, Harvard Medical School, USA 1987-1992 Research Fellow, Department of Transplant Immunology, Molecular Biology, Harvard Medical School, Boston, USA 1983-1987 Resident, Deparment of Medicine, Free University Berlin |
| Scientific Activities: | 2006-present Academic Consultant of the Nephrology Institute, Changzheng Medical University, Shanghai, China 2002-2004 Panel Member, Welcome Trust, London |
Honors
| Honors and Awards: | 2011 Lillian Jean Kaplan International Prize for Advancement in the Understanding of Polycystic Kidney Disease |
Publications
| Selected Publications: | Thien A, Prentzell MT, Holzwarth B, et al. TSC1 Activates TGF-beta-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition. Dev Cell 2015; 32(5): 617-30. Abstract Hoff S, Halbritter J, Epting D, et al. ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet 2013; 45(8): 951-6. Abstract Lienkamp SS, Liu K, Karner CM, et al. Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension. Nat Genet 2012; 44(12): 1382-7. Abstract Chaki M, Airik R, Ghosh AK, et al. Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling. Cell 2012; 150(3): 533-48. Abstract Lienkamp S, Ganner A, Boehlke C, et al. Inversin relays Frizzled-8 signals to promote proximal pronephros development. Proc Natl Acad Sci U S A 2010; 107(47): 20388-93. Abstract Boehlke C, Kotsis F, Patel V, et al. Primary cilia regulate mTORC1 activity and cell size through Lkb1. Nat Cell Biol 2010; 12(11): 1115-22. Abstract Walz G, Budde K, Mannaa M, et al. Everolimus in patients with autosomal dominant polycystic kidney disease. N Engl J Med 2010; 363(9): 830-40. Abstract Ganner A, Lienkamp S, Schafer T, et al. Regulation of ciliary polarity by the APC/C. Proc Natl Acad Sci U S A 2009; 106(42): 17799-804. Abstract Skouloudaki K, Puetz M, Simons M, et al. Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development. Proc Natl Acad Sci U S A 2009; 106(21): 8579-84. Abstract Simons M, Gloy J, Ganner A, et al. Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat Genet 2005; 37(5): 537-43. Abstract
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SGBM PhD students
| SGBM PhD students: |
Alumni Alexandra Bona (10/2016 - 07/2021) Yun Hee Kim (03/2009 - 06/2013) Sylvia Hoff (01/2009 - 09/2013) |
