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Martin Schwemmle Profile Page
Martin Schwemmle

Contact

Lab: Prof. Dr. Martin Schwemmle
Department: Institute of Virology
Department for Medical Microbiology and Hygiene
Phone: 203 6526
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage: www.uniklinik-freiburg.de/virologie-en/research/research-teams/martin-schwemmle-team.html
PhD positions available: YES
Research Area: Immunology and Virology
Research Interests: - Species transmission of highly pathogenic influenza A viruses
- Emerging bat viruses
- Innate immunity
- Neurotropic viruses

CV

Education & Training: 1983-1989: Diploma in Biology, Institute of Biology III, University of Freiburg, Germany
1992: Dr. rer. nat., Biology, Institute of Biology III, University of Freiburg, Germany
1999: Habilitation, Virology, Department of Virology, University of Freiburg
Employment & Experience: 1992-1994: Research Fellow (Molecular Virology and Biochemistry), Department of Virology, University of Freiburg, Germany
1995-1997: Visiting scientist (Neurovirology) at the Institute of Neurology, UC-Irvine, USA
1997-2001: Group leader (Molecular Virology and Cell Biology), University of Freiburg, Germany
2002-2003: Group leader (Molecular Virology and Cell Signaling), Institute of Virology, University Zürich, Switzerland
9/2003-present: Professor (Molecular Virology), Department of Virology, University of Freiburg, Germany
Scientific Activities: 1996 Member of the German Society of Virology (GFV)
1997 Member of the American Society of Virology (ASV)
2005 Member of the American Society of Microbiology (ASM)
2004-2005 Guest Editor, Virus Research
2008 Editor of Archives of Virology
1997 Member of the European Society for Virology
2013 Editorial board JBC
2014 Editorial board JVI

Honors

Honors and Awards:

1992: Hans-Griesebach Award for PhD-thesis
1994: Isaac-Lindenmann Fellowship
1995: DFG research fellowship
1997: DFG Habilitation fellowship
2014: Fulbright fellowship

 

Patents:

PCT/EP2009/055632 INFLUENZA A AND B VIRUS REPLICATION-INHIBITING PEPTIDES

Publications

Selected Publications:

Juozapaitis M, Aguiar Moreira É, Mena I, Giese S, Riegger D, Pohlmann A, Höper D, Zimmer G, Beer M, García-Sastre A, Schwemmle M. (2014) An infectious bat-derived chimeric influenza virus harbouring the entry machinery of an influenza A virus. Nat Commun. 5:4448. Abstract

Mänz B, Dornfeld D, Götz V, Zell R, Zimmermann P, Haller O, Kochs G, Schwemmle M. (2013) Pandemic influenza A viruses escape from restriction by human MxA through adaptive mutations in the nucleoprotein. PLoS Pathog. 9(3):e1003279. Abstract

Wu YJ, Schulz H, Lin CC, Saar K, Patone G, Fischer H, Hübner N, Heimrich B, Schwemmle M. (2013) Borna disease virus-induced neuronal degeneration dependent on host genetic background and prevented by soluble factors. Proc Natl Acad Sci U S A. 29;110(5):1899-904. Abstract

Matsumoto Y, Hayashi Y, Omori H, Honda T, Daito T, Horie M, Ikuta K, Fujino K, Nakamura S, Schneider U, Chase G, Yoshimori T, Schwemmle M, Tomonaga K. (2012) Bornavirus closely associates and segregates with host chromosomes to ensure persistent intranuclear infection. Cell Host Microbe. 11(5):492-503. Abstract

Mänz B, Brunotte L, Reuther P, Schwemmle M. (2012) Adaptive mutations in NEP compensate for defective H5N1 RNA replication in cultured human cells. Nat Commun. 3:802. Abstract

Prat CM, Schmid S, Farrugia F, Cenac N, Le Masson G, Schwemmle M, Gonzalez-Dunia D. (2009) Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity. PLoS Pathog. 2009 May;5(5):e1000425. Abstract

Ghanem A, Mayer D, Chase G, Tegge W, Frank R, Kochs G, Garcia-Sastre A, Schwemmle M.(2007) Peptide-mediated interference with the influenza A virus polymerase. J Virol 81:7801-4. Abstract

Schmid S, Mayer D, Schneider U, Schwemmle M. (2007) Functional characterization of the major and minor phosphorylation sites of the P protein of Borna disease virus. J Virol 81:5497-507. Abstract

Schneider U, Schwemmle M and Staeheli P (2005) Genome trimming: A unique strategy for replication control employed by Borna disease virus. PNAS 102:3441-3446. Abstract

Schwemmle, M., C. Jehle, S. Formella, and P. Staeheli. 1999. Sequence similarities between human bornavirus isolates and laboratory strains question human origin. Lancet 354:1973-4. Abstract

SGBM PhD students

SGBM PhD students:

Track 1:

Thiprampai Thamamongood (since January 2017)

Okikiola Olajide (since January 2018)

 

Track 2:

Hardin Bolte (since July 2015)

 


Alumni

Track 1:

Yuan-Ju Wu (09/2007 - 09/2011)

Etori Moreira (01/2013 - 02/2017)

Alexandra Dudek (01/2014 - 12/2017)

 

Track 2:

Geoffrey Chase (09/2006 - 09/2010)

Kerstin Wunderlich (02/2008 - 12/2010)

Chia-Ching Lin (11/2009 - 07/2013)

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