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Contact
Lab: | Prof. Dr. Robert Thimme |
Department: | Department of Medicine University Medical Center |
Phone: | 270 32800 |
E-mail: | This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
Lab homepage: | www.uniklinik-freiburg.de/medizin2/forschung.html |
PhD positions available: | YES |
Research Area: | Immunology and Virology |
Research Interests: | Identification and characterization of virus- and tumor-specific CD4+ and CD8+ T cell responses during HBV and HCV-infection and hepatocellular carcinoma. |
CV
Education & Training: | 1989-1996: MD, Medicine, Free University of Berlin and Albert-Ludwigs-University Freiburg, Germany |
Employment & Experience: | 1993-1995: Doctoral thesis in the Department of Virology (Head: Prof. Otto Haller), University of Freiburg, honor: summa cum laude 1995: Clinical Observer at the Memorial Sloan Kettering Cancer Center (Head: Prof. John Mendelsohn), New York (USA) 1996-1998: MD in the Department of Medicine II (Head: Prof. Hubert E. Blum), University of Freiburg 1998-2001: Research Associate at the Scripps Research Institute (Head: Prof. Francis V. Chisari) 2002-present: Junior Group leader in the Emmy Noether Programme of the Deutsche Forschungsgemeinschaft (DFG), Department of Medicine II (Head: Prof. Hubert E. Blum), University of Freiburg 2004-present: Junior Professor for hepatitisvirusinfections in the Department of Medicine II (Head: Prof. Hubert E. Blum), University of Freiburg 2009-2014: W2/W3 Heisenberg-Professor for Hepatology 10/2013: Director Clinic for Medicine II |
Scientific Activities: | 2005-present: Editorial Board, Journal of Clinical Investigation, Gastroenterology, Journal of Infectious Diseases, World Journal of Gastroenterology, Journal of Hepatology, Langenbeck´s Archives of Surgery, Frontiers in Virology 1999-present: Member, American Association for the Study of Liver Disease, European Society of Clinical Virology, German Association for Internal Medicine, German Association for the Study of Liver Diseases, The European Association for the Study of the Liver, German Association for Gastroenterology 2000-present: regular reviewer of Nature Medicine, Journal of Clinical Investigation, Journal of Virology, Journal of Immunology, Gastroenterology, Hepatology, European Journal of Immunology, Journal of Infectious Diseases, Journal of Clinical Microbiology, The Lancet, Blood, Liver Transplantation, Journal of General Virology, Journal of Interferon and Cytokine Research, Vaccine, Liver International, International Journal of Virology, Deutsche Medizinische Wochenschrift, Zeitschrift für Gastroenterologie 2000-present: regular reviewer for Grant agencies DFG, Swiss National Science Foundation, Welcome Trust, INSERM, French National Cancer Institute, DAAD, Medical Research Council, Dutch Digestive Foundation 2006-2007: programme committee German Association for the study of liver diseases (GASL) 2009-2012: Scientific Secretary of the German Association for the Study of the Liver (GASL) |
Honors
Honors and Awards: | 1994 Ludwig Heilmeyer Price of the University of Freiburg for best experimental doctoral thesis |
Publications
Selected Publications: | Nitschke K, Flecken T, Schmidt J, Gostick E, Marget M, Neumann-Haefelin C, Blum HE, Price DA, Thimme R. Tetramer enrichment reveals the presence of phenotypically diverse hepatitis C virus-specific CD8+ T cells in chronic infection. J Virol. 2015 Jan;89(1):25-34. doi: 10.1128/JVI.02242-14. Epub 2014 Oct 15. Abstract Bengsch B, Martin B, Thimme R. Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation. J Hepatol. 2014 Dec;61(6):1212-9. doi: 10.1016/j.jhep.2014.07.005. Epub 2014 Jul 10. PubMed PMID: 25016223. Abstract Seigel B, Bengsch B, Lohmann V, Blum HE, Thimme R. (2013) Factors that determine the antiviral efficacy of HCV-specific CD8+ T cells ex vivo. Gastroenterology, 144(2):426-36. Abstract |
SGBM PhD students
SGBM PhD students: |
Alumni Track 1: Bertram Bengsch (04/2009 - 02/2013) Juandy Jo (11/2007 - 05/2010)
Tobias Flecken (01/2011 - 07/2015) Eva Billerbeck (07/2005 - 03/2009) Bianca Seigel (06/2008 - 05/2012) Alexander Hoh (04/2012 - 03/2017) Dominik Wieland (10/2013 - 07/2017) |