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Contact
| Lab: | PD Dr. Nils Wiedemann |
| Department: | Institute of Biochemistry and Molecular Biology |
| Phone: | 203 5280 |
| E-mail: | This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
| Lab homepage: | www.biochemie.uni-freiburg.de/ag/wiedemann/research/research |
| BIOSS Excellence Cluster: | Project leader |
| PhD positions available: | YES |
| Research Area: | Protein Structure and Function |
| Research Interests: | Mitochondrial biogenesis and sorting of mitochondrial membrane proteins. |
CV
| Education & Training: | 1993-1995: Prediploma in Chemistry, Johann Wolfgang Goethe-University Frankfurt, Germany 1995-1999: Diploma in Chemistry, Albert-Ludwigs-University Freiburg, Germany 1996-1997: Master classes in Biochemistry, Cell Biology & Molecular Biology, University of Massachusetts, Amherst, USA 2002: Dr. rer. nat., Faculty of Biology, Albert-Ludwigs-University Freiburg, Germany 2010: Habilitation, Faculty of Medicine, Albert-Ludwigs-University Freiburg, Germany |
| Employment & Experience: | 2001: Yeast Genetics Course, Cold Spring Harbor Laboratory, USA 2002-2004: Postdoctoral Fellow in Biochemistry, University of Freiburg 2004-2010: Group leader, Institute for Biochemistry and Molecular Biology, University of Freiburg 2006: Visiting Scientist, La Trobe University, Melbourne, Australia 2010: Privatdozent (Habilitation), Faculty of Medicine, University of Freiburg 2013: Academic director, Institute for Biochemistry and Molecular Biology, University of Freiburg |
| Scientific Activities: | 2000-present: Member of the German Society for Biochemistry and Molecular Biology (GBM), Frankfurt, Germany 2012-present: Project leader of the Excellence Cluster Centre of Biological Signalling Studies (BIOSS), University of Freiburg 2015-present: Member of Collaborative Research Centre ‘Kidney Disease - from Genes to Mechanisms’ (KIDGEM, SFB 1140), University of Freiburg |
Honors
| Honors and Awards: | 2015: ERC consolidator grant
2001: Fellowship of the scientific society Freiburg for participation in the yeast genetics course, Cold Spring Harbor Laboratory, USA
2002: Summa cum laude, University of Freiburg
2003: PhD Award ‘Hans Grisebach Dissertationspreis’, Faculty of Biology, University of Freiburg
2007: Young Investigator Award, German Society for Biochemistry and Molecular Biology (GBM), Frankfurt
2011: Eugen-Graetz-Price for Research, Faculty of Medicine, University of Freiburg |
Publications
| Selected Publications: | Qiu, J., Wenz, L.S., Zerbes, R.M., Oeljeklaus, S., Bohnert, M., Stroud, D.A., Wirth, C., Ellenrieder, L., Thornton, N., Kutik, S., Wiese, S., Schulze-Specking, A., Zufall, N., Chacinska, A., Guiard, B., Hunte, C., Warscheid, B., van der Laan, M., Pfanner, N.*, Wiedemann, N.*, Becker, T. (2013) Coupling of Mitochondrial Import and Export Translocases by Receptor-Mediated Supercomplex Formation. Cell. 154, 596–608. (* corresponding) Abstract Gebert, N., Gebert, M., Oeljeklaus, S., von der Malsburg, K., Stroud, D.A., Kulawiak, B., Wirth, C., Zahedi, R.P., Dolezal, P., Wiese, S., Simon, O., Schulze-Specking, A., Truscott, K.N., Sickmann, A., Rehling, P., Guiard, B., Hunte, C., Warscheid, B., van der Laan, M., Pfanner, N., Wiedemann, N. (2011) Dual Function of Sdh3 in the Respiratory Chain and TIM22 Protein Translocase of the Mitochondrial Inner Membrane. Mol Cell. 44, 811–818. Abstract Stroud, D.A., Oeljeklaus, S., Wiese, S., Bohnert, M., Lewandrowski, U., Sickmann, A., Guiard, B., van der Laan, M., Warscheid, B., Wiedemann, N. (2011) Composition and topology of the endoplasmic reticulum-mitochondria encounter structure. J Mol Biol. 413, 743–750. Abstract Kutik, S., Stojanovski, D., Becker, L., Becker, T., Meinecke, M., Krüger, V., Prinz, C., Meisinger, C., Guiard, B., Wagner, R., Pfanner, N. and Wiedemann, N. (2008) Dissecting membrane insertion of mitochondrial beta-barrel proteins. Cell. 132, 1011-1024. Abstract Kutik, S., Rissler, M., Guan, X.L., Guiard, B., Shui, G., Gebert, N., Heacock, P.N., Rehling, P., Dowhan, W., Wenk, M.R., Pfanner, N., Wiedemann, N. (2008) The translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis. J Cell Biol. 183, 1213–1221. Abstract Gebert, N., Chacinska, A., Wagner, K., Guiard, B., Koehler, C.M., Rehling, P., Pfanner, N. and Wiedemann, N. (2008) Assembly of the three small Tim proteins precedes docking to the mitochondrial carrier translocase. EMBO Rep. 9, 548-554. Abstract Becker, T., Pfannschmidt, S., Guiard, B., Stojanovski, D., Milenkovic, D., Kutik, S., Pfanner, N., Meisinger, C. and Wiedemann, N. (2008) Biogenesis of the Mitochondrial TOM Complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem. 283, 120-127. Abstract Meisinger, C., Pfannschmidt, S., Rissler, M., Milenkovic, D., Becker, T., Stojanovski, D., Youngman, M.J., Jensen, R.E., Chacinska, A., Guiard, B., Pfanner, N. and Wiedemann, N. (2007) The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria. EMBO J. 26, 2229-2239. Abstract Wiedemann, N., Urzica, E., Guiard, B., Müller, H., Lohaus, C., Meyer, H.E., Ryan, M.T., Meisinger, C., Mühlenhoff, U., Lill, R. and Pfanner, N. (2006) Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J. 25, 184-195. Abstract Wiedemann, N., Kozjak, V., Chacinska, A., Schönfisch, B., Rospert, S., Ryan, M.T., Pfanner, N. and Meisinger, C. (2003) Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature. 424, 565-571. Abstract |
