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Contact
| Lab: | Prof. Dr. Oliver Einsle |
| Department: | Institute of Biochemistry |
| Address: | Albertstraße 21 79104 Freiburg |
| Phone: | +49 761 203 6058 |
| E-mail: | This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
| Lab homepage: | www.xray.uni-freiburg.de |
| BIOSS Excellence Cluster: | Associated Member |
| PhD positions available: | YES |
| Research Area: | Protein Structure and Function |
| Research Interests: | Structure and Function of Membrane Proteins and Metalloproteins |
CV
| Education & Training: | 1991-1996: Diploma in Biology at Universität Konstanz 2000: Dr. rer. nat. in Biology Biophysics & Biochemistry at Universität Konstanz |
| Employment & Experience: | 2000-2001: Postdoctoral fellow with R. Huber, MPI for Biochemistry, Martinsried, Germany 2001-2003: Postdoctoral fellow with D.C. Rees, California Institute of Technology, Pasadena, USA 2003-2008: Junior professor for Protein Crystallography, University of Göttingen, Germany 2008-present: Full Professor and Chair of Biochemistry, University of Freiburg, Germany |
| Scientific Activities: | 1998-present: Member of the German Association for General and Applied Microbiology (VAAM) 1998-present: Member of the Society for Biochemistry and Molecular Biology (GBM) 1999-present: Member of the Society for Biological Inorganic Chemistry (SBIC) 2003: Co-organizer of the “International Symposium on Copper in Biology” 2006: Co-organizer of the “9th Heart of Europe Meeting on Biocrystallography” 2007-present: Member of the American Chemical Society (ACS) 2012: Co-organizer of the „17th European Bioenergetics Conference (EBEC)“ 2012-present: Speaker of the study group „Structural Biology“ of the GBM 2013: Co-organizer of the “27th Rhine-Knee Meeting on Biocrystallography” 2014: Organizer of the “5th Murnau Conference on Structural Biology” |
Honors
| Honors and Awards: | 2001: Doctoral Award of the Society for General and Applied Microbiology (VAAM) 2001: Byk Award, Hebert-Quandt-Foundation, Altana AG 2005: EMBO Young Investigator 2012: ERC starting grant 2013: SBIC Early Career Award 2013: Johann Griess Lectureship, Royal Society of Chemistry, East Midlands Section |
Publications
| Selected Publications: | Hermann, B., Kern, M., La Pietra, L., Simon, J. & Einsle, O. The octahaem MccA is a haem c–copper sulfite reductase. (2015) Nature, Feb 2. doi: 10.1038/nature14109. [Epub ahead of print]. Abstract Spatzal, T., Perez, K.A., Einsle, O., Howard, J.B. & Rees, D.C. Ligand binding to the FeMo-cofactor: Structures of CO-bound and reactivated nitrogenase. (2014) Science, 345, 1620-1623. Abstract Lü W, Schwarzer NJ, Du J, Gerbig-Smentek E, Andrade SLA, Einsle O. Structure and mechanism of the nitrite channel NirC from Salmonella typhimurium. (2012) Proc. Natl. Acad. Sci. USA, 109, 18395-18400. Abstract Spatzal T, Aksoyoglu M, Zhang L, Andrade SLA, Schleicher E, Weber S, Rees DC, Einsle O. Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor. (2011) Science, 334, 940. Abstract Du J, Say RF, Lü W, Fuchs G, Einsle O. Active site remodeling in the bifunctional fructose-6-bisphosphate aldolase/phosphatase. (2011) Nature, 478, 534-537. Abstract Pomowski A, Zumft WG, Kroneck PMH, Einsle O. N2O binding at a [4Cu:2S] copper-sulfur cluster in nitrous oxide reductase. (2011) Nature 477, 234-237. Abstract Lü W, Du J, Wacker T, Gerbig-Smentek E, Andrade SLA, Einsle O. pH-dependent gating in a FocA formate channel. (2011) Science, 332, 352-354. Abstract Andrade SLA, Dickmanns A, Ficner R, Einsle O. Crystal Structure of the Archaeal Ammonium Transporter Amt-1 from Archaeoglobus fulgidus. (2005). Proc. Natl. Acad. Sci. USA, 102, 14994-14999. Abstract Einsle O, Tezcan FA, Andrade SL, Schmid B, Yoshida M, Howard JB, Rees DC. Nitrogenase MoFe protein at 1.16 Å resolution: A central ligand in the FeMo cofactor. (2002) Science 297, 1696-1700. Abstract Einsle O, Messerschmidt A, Stach P, Bourenkov GP, Bartunik HD, Huber R, Kroneck PMH. Structure of cytochrome c nitrite reductase. (1999) Nature 400, 476-480. Abstract |
SGBM PhD students
| SGBM PhD students: | Alumni Track 1:
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