|Lab:||Prof. Dr. Marlene Bartos|
|Department:||Lichtenbergprofessor for cellular and systemic Neurophysiology
Institute for Physiology I
|Address:||University Freiburg Engesser Straße 4
|Phone:||0049 (0)761 203 5194|
|PhD positions available:||YES|
|Research Interests:||Our group is interested in the cellular basis of information processing in the brain. The goal is to understand how information is encoded, stored and retrieved from neuronal networks.
Our objectives are:
1. To determine cellular and molecular mechanisms underlying synaptic communication among cortical neurons.
2. To examine the cellular basis of network synchronization in the healthy and diseased brain.
3. To identify the rules for induction of synaptic plasticity.
4. To elucidate the role of neuron types in cognition and behaviour.
|Education & Training:||1984-1990 Undergraduate and graduate studies in Biology, Technical University of Braunschweig
1991 Diploma thesis at the Technical University Munich, Institute for Zoology (Prof. H-W Honegger)
1991-1994 PhD at the Technical University Munich, Institute for Zoology
|Employment & Experience:||1995-1998 Postdoctoral Research Associate, University of Pennsylvania (USA), School of Medicine, Department of Neuroscience, (Prof. MP Nusbaum)
1998-2007 Senior Scientist (C1) University Freiburg, Institute of Physiology I (Prof. P Jonas)
2002-2003 Maternity leave
2006-2007 ‘Habilitation’ in Physiology with the topic: Functional role of inhibitory synapses for the generation and coordination of oscillatory network activity
2007-2009 Reader (Associate Professor) at the University of Aberdeen (Scotland, UK), Institute of Medical Sciences (IMS)
2009-2010 Professor (Personal Chair) at the University of Aberdeen (IMS)
Since 2010 Lichtenberg Professor (W3) at the University of Freiburg
|Scientific Activities:||April 2004 Member of the organizing board for the ‘Annual Neurex Meeting 2004’ with the topic ‘Neuronal connectivity: development and function’ (Freiburg).
July 2004 Course Director of the ‘International ELTEM Workshop 2004’ with the topic ‘Interneurons, GABAergic transmission and network dynamics’ (Freiburg).
March 2005 Principal organizer of the symposium: ‘Network oscillations and their underlying mechanisms’ at the ‘German Physiology Meeting’ (Göttingen).
October 2005 Member of the organizing board for the ‘First national meeting of the Bernstein Centers for Computational Neuroscience’ (BCCNs) (Freiburg).
February 2008 Chair of the 4th International Conference of the ‘Volkswagenstiftung’ ‚Dynamics and adaptivity of neuronal systems: integrative approaches to analyse cognitive functions’. University Tübingen.
June 2009 Lecturer at the Okinawa ‘Computational Neuroscience course 2009’ in Okinawa (Japan) (Organizer: Prof. E. De Shutter).
October 2010 Invited speaker at the Gordon conference
Since 2000 Reviewer for international journals: Science, Journal of Neuroscience, Brain Research, Journal of Computational Neuroscience, European Journal of Neuroscience and Journal of Physiology.
Reviewer for the ‘Wellcome Trust’, the ‘Leverhulme Trust’, the ‘Royal Society’, the ‘BBSRC’ and the ‘Human Frontier Science Program’ (HFSP), the Canadian NIH
Executive Board Member of the Excellence Initiative "Brain Links - Brain Tools (BL-BT)"
1992-1994 Women’s representative in the Faculty of Biology, Geography and Chemistry at the Technical University of Munich.
Since 2004 Member of the ‘Mentoring Program’ at the University Freiburg.
Since 2010 ‘Stellvertretende Gleichstellungsbauftragte’ of the University of Freiburg, Medical Faculty
October 2011 Symposium ‘Hat Wissenschaft ein Geschlecht’ Beitrag zur Exzellenzinitiative 2011, Medical University Vienna, Austria
|Honors and Awards:||
1992-1994 Fellowship of the ‘Friedrich-Ebert Stiftung’
Strüber M, Jonas P, Bartos M (2015) Strength and duration of perisomatic GABAergic inhibition depend on distance between synaptically connected cells. PNAS USA 112:1220-1225. Abstract
Sauer JF, Strüber M, Bartos M (2015) Impaired fast-spiking interneuron function in a genetic mouse model of depression. Elife. doi: 10.7554/eLife.04979. Abstract
Elgueta C, Köhler J, Bartos M (2015) Persistent discharges in dentate gyrus perisoma-inhibiting interneurons require hyperpolarization-activated cyclic nucleotide-gated channel activation. J Neurosci 35:4131-4139. Abstract
Hainmüller T, Krieglstein K, Kulik A, Bartos M (2014) Joint CP-AMPA and group I mGlu receptor activation is required for synaptic plasticity in dentate gyrus fast-spiking interneurons. PNAS USA 111:13211-13216. Abstract
Hosp JA, Strüber M, Yanagawa Y, Obata K, Vida I, Jonas P, Bartos M. (2014) Morpho-physiological criteria divide dentate gyrus interneurons into classes. Hippocampus 24: 189-203. Abstract
Savanthrapadian S, Meyer T, Elgueta C, Booker SA, Vida I, Bartos M. (2014) Synaptic properties of SOM- and CCK-expressing cells in dentate gyrus interneuron networks. J Neurosci 24:8197-8209. Abstract
Sauer J-F, Strüber M, Bartos M (2012) Interneurons provide circuit-specific depolarization and hyperpolarization. J Neurosci 32:4224-4229. Abstract
Murray AJ, Sauer JF, Riedel G, McClure C, Ansel L, Cheyne L, Bartos M, Wisden W, Wulff P. (2011) Parvalbumin-positive hippocampal interneurons are required for spatial working but not reference memory. Nat Neurosci 14: 297-299. Abstract
Bartos M, Vida I, Jonas P (2007) Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks. Nat Rev Neurosci 8:45-56. Abstract
Vida I, Bartos M, Jonas P (2006) Shunting inhibition improves robustness of gamma oscillations in hippocampal interneuron networks by homogenizing firing rates. Neuron 49:107-117 (equal contribution of the authors). Abstract
SGBM PhD students
|SGBM PhD students:||