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Susana Andrade Profile Page
Susana Andrade


Lab: Prof. Dr. Susana Andrade
Department: Institute of Biochemistry
Address: Albertstrasse 21 79104 Freiburg
Phone: (+49) 761 203 8719
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:
PhD positions available: YES
Research Area: Synthetic Biology and Signalling
Research Interests: Structure, function and regulation of membrane proteins involved in ion transport and sensing mechanisms


Education & Training: 1991-1996: Diploma in Biochemistry at Classic University of Lisbon, Portugal
1998-2002: Dr. rer. nat. in Biochemistry/Biophysics at New University of Lisbon, Portugal
Employment & Experience: 1996-1997: Young Investigator fellow, New University of Lisboa, Lisboa, Portugal
1997: Visiting Investigator, Lemonosov Moscow State University, Moscow, Russia
1999: Visiting Investigator, Technical University of Lisboa, Lisboa, Portugal
2001-2002: Postdoc fellow, California Institute of Technology, Pasadena, USA
2001: Visiting Investigator, University of California Davis, USA
2003-2005: Postdoc fellow, University of Göttingen, Germany
2006-2011: Emmy-Noether Group Leader, University of Freiburg, Germany
2012-2017: W2 Professor, University of Freiburg, Germany
since 2018: W3 professor for Biochemistry, University of Freiburg, Germany
Scientific Activities: Memberships:
1995-present: Society for Biological Inorganic Chemistry (SBIC)
2003-present: International Electron Paramagnetic Resonance Society
2006-present: American Chemical Society (ACS)
2007-present: German Society for Biochemistry and Molecular Biology (GBM)
2007-present: American Society for Microbiology (ASM)
2010-present: Biophysical Society
2006-2008: Intern. Max Planck Res. School and Georg-August Univ. (Molecular Biology Master/Ph.D. Program)
2007-2008: Göttingen Graduate School (Neurosciences and Molecular Biology: Biomolecules, Structure, Function and Dynamics Program)
2007-2008: Invited Junior Group Member of the Göttingen Center for Molecular Biosciences (GZMB)
2010-present: Invited Member of ‘AcademiaNet - Internet Portal for Excellent Researchers’
2010-present: Associate Member of the DFG Research Unit ‘Diversity of Asymmetric Thiamine Catalysis’ (Chair: Prof. Michael Müller; DFG-FOR 1296)
2010-present: DFG-IRTG ‘Membrane Proteins and Biological Membranes’ (Chair: Prof. Thorsten Friedrich; DFG-GRK 1478)
2011-present: Associate Member of BIOSS Center for Biological Signaling Studies, University of Freiburg, Germany
2011-present: Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Germany
2012-2021: Member of the Executive Board of the Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Germany
since 2019: Full member of BIOSS Center for Biological Signaling Studies, University of Freiburg, Germany


Honors and Awards:

2015               Eugen-Graetz-Preis
2006-present  Emmy-Noether Fellow, DFG (AN 676/1)
2004-2005      Postdoctoral Fellow, Marie Curie Intra-European Fellowships (FP6-500739)
1998-2001      Ph.D. Research Fellowship, Portuguese Sci. Technol. Foundation (FCT)
1996-1997      Young Scientific Research Fellowship, Nat. Sci. Technol. Res. Council (JNICT), Program PRAXIS XXI
1995                Undergraduate Research Award, PRODEP/95


Selected Publications:

Pflüger T, Hernández CF, Lewe P, Frank F, Mertens H, Svergun D, Baumstark MW, Lunin VY, Jetten MSM, Andrade SLA. Signaling ammonium across membranes through an ammonium sensor histidine kinase. Nat Commun. 2018 Jan 11;9(1):164.  Abstract

Sippel D, Rohde M, Netzer J, Trncik C, Gies J, Grunau K, Djurdjevic I, Decamps L, Andrade SLA, Einsle O. A bound reaction intermediate sheds light on the mechanism of nitrogenase. Science. 2018 Mar 30;359(6383):1484-1489.  Abstract

Wacker T, Garcia-Celma JJ, Lewe P, Andrade SL. Direct observation of electrogenic NH4(+) transport in ammonium transport (Amt) proteins. Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9995-10000. Abstract

Spatzal T, Einsle O, Andrade SL. Analysis of the magnetic properties of nitrogenase FeMo cofactor by single-crystal EPR spectroscopy. Angew Chem Int Ed Engl. 2013 Sep 16;52(38):10116-9. Abstract

De Michele R, Ast C, Loqué D, Ho CH, Andrade S, Lanquar V, Grossmann G, Gehne S, Kumke MU, Frommer WB. Fluorescent sensors reporting the activity of ammonium transceptors in live cells. Elife. 2013 Jul 2;2:e00800.  Abstract

Lü W, Schwarzer NJ, Du J, Gerbig-Smentek E, Andrade SL, Einsle O. Structural and functional characterization of the nitrite channel NirC from Salmonella typhimurium. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18395-400.  Abstract

Lü W, Du J, Schwarzer NJ, Gerbig-Smentek E, Einsle O, Andrade SL. The formate channel FocA exports the products of mixed-acid fermentation. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13254-9.  Abstract

Maier S, Schleberger P, Lü W, Wacker T, Pflüger T, Litz C, Andrade SL. Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. PLoS One. 2011;6(10):e26327. Abstract

Lü W, Du J, Wacker T, Gerbig-Smentek E, Andrade SL, Einsle O. pH-dependent gating in a FocA formate channel. Science. 2011 Apr 15;332(6027):352-4.  Abstract

Andrade SL, Dickmanns A, Ficner R, Einsle O. Crystal structure of the archaeal ammonium transporter Amt-1 from Archaeoglobus fulgidus. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):14994-9.  Abstract

SGBM PhD students

SGBM PhD students:

Maria Agostina Di Renzo (since January 2017)

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