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Principal Investigators

Displaying 1 - 16 of 16
Name Research Area & Research interests Memberships
Asifa Akhtar's picture Asifa Akhtar
Max Planck Institute of Immunobiology and Epigenetics 		Protein Structure and Function

- Chromatin and epigenetic regulation

CIBSS, SFB1381, SFB1425
Sonja Albers's picture Sonja Albers
Institute of Biology II 		Protein Structure and Function

- Biogenesis of the archaeal cell envelope / Assembly of macromolecular structures in the archaeal cell envelope / Regulation of archaellum biosynthesis / Signaltransduction cascades and the involvement of protein phosphorylation / Development of genetic tools for different archaeal species

CIBSS, SFB1381
Susana Andrade's picture Susana Andrade
Institute of Biochemistry 		Protein Structure and Function

- Structure, function and regulation of membrane proteins involved in ion transport and sensing mechanisms

Matthias Boll's picture Matthias Boll
Institute of Biology II 		Protein Structure and Function

- Enzymes and metabolites involved in the degradation of aromatic pollutants in anaerobic bacteria.

SFB1381
Oliver Einsle's picture Oliver Einsle
Institute of Biochemistry 		Protein Structure and Function

- Structure and Function of Membrane Proteins and Metalloproteins

SFB1381
Thorsten Friedrich's picture Thorsten Friedrich
Institute of Biochemistry 		Protein Structure and Function

- Mitochondria and bacteria respiratory complex I, the first complex of cell respiration

Carola Hunte's picture Carola Hunte
Institute for Biochemistry and Molecular Biology 		Protein Structure and Function

- Structure and mechanism of medically relevant membrane proteins, bioenergetics, ion transport, biological signalling, structural lipids.

CIBSS, SFB1381, SFB1453
Hans-Georg Koch's picture Hans-Georg Koch
Institute of Biochemistry and Molecular Biology 		Protein Structure and Function

- Our work is focused on bacterial cell biology. By biochemical methods and molecular imaging approaches we explore targeting pathways of proteins and mRNAs, we determine how cells respond to stress conditions and how protein machineries are assembled.

SFB1381
Maja Köhn's picture Maja Köhn
Institute of Biology III 		Protein Structure and Function

- Elucidation of the functions and molecular mechanisms of the cancer-promoting phosphatase PRL-3 and the ubiquitous phosphatase PP1 / Development of inhibitors and activators for phosphatases

CIBSS, SFB1381
Claudine Kraft's picture Claudine Kraft
Institute of Biochemistry and Molecular Biology 		Protein Structure and Function

- Our group aims at understanding how the molecular machinery of autophagy, the cellular waste disposal system, works.

CIBSS, SFB1381
Chris Meisinger's picture Chris Meisinger
Institute of Biochemistry and Molecular Biology 		Protein Structure and Function

- Signaltransduction in mitochondrial protein import / Mitochondrial signal switches in tumor diseases / Mitochondrial protein quality control in Alzeimer’s disease

CIBSS, SFB1381
Nikolaus Pfanner's picture Nikolaus Pfanner
Institute of Biochemistry and Molecular Biology 		Protein Structure and Function

- Mechanisms of intracellular protein sorting with a focus on targeting and assembly of mitochondrial proteins.

CIBSS
Raphael Reuten's picture Raphael Reuten
Institute for Clinical and Experimental Pharmacology and Toxicology, Dept. I 		Protein Structure and Function

- Extracellular matrix (ECM) architecture / Impact of mechanical and chemical ECM properties on tumor progression / Identifying metastasis predisposing ECM features for diagnostic and therapeutic options

Khaled Selim's picture Khaled Selim
Institute of Biology II 		Protein Structure and Function

- Metabolic Engineering / Synthetic pathways / Molecular and structural mechanisms for coordination of carbon/nitrogen metabolism in prokaryotes / Cell signaling with special emphasis on PII signaling superfamily and second messengers signaling (c-di-AMP, c-di-GMP and Ca2+ signaling) / Membrane transporters / Cyanobacterial multicellularity and developmental processes.

SFB1381
Nora Vögtle's picture Nora Vögtle
Centre for Molecular Biology Heidelberg, University of Heidelberg 		Protein Structure and Function

- Our group wants to understand the role of mitochondrial proteases in the maintenance of the mitochondrial proteome. We use yeast, mammalian and patient cells to investigate the pathophysiological consequences of dysfunctions in these proteases that result in severe neurodegenerative diseases and cardiomyopathies.

CIBSS, SFB1381
Nils Wiedemann's picture Nils Wiedemann
Institute of Biochemistry and Molecular Biology 		Protein Structure and Function

- Biogenesis of mitochondrial beta-barrel membrane proteins and alpha-helical outer membrane proteins / Import, sorting, insertion and assembly of mitochondrial alpha-helical inner membrane proteins / Assembly of respiratory chain complexes / Analysis of the mitochondrial proteome in yeast and human cells.

CIBSS, SFB1381