Principal Investigators

Displaying 1 - 14 of 14
Name Research Area & Research interests Memberships
Stefan Ehl's picture Stefan Ehl
Centre for Chronic Immunodeficiency, University Medical Center
Immunology and Virology

- The group „Human T-cell immunodeficiency“ works at the interface of clinical and basic research focussing on human T cell immunity. The projects range from the identification of novel gene defects followed by pathophysiological studies to the development of novel diagnostic tools and therapies.

Florian Full's picture Florian Full
Institute of Virology
Immunology and Virology

- Elucidating the role of the germline transcription factor DUX4 in herpesviral infections / Evaluate the transcription factor DUX4 as novel target for anti-herpesviral therapy / Characterize the epigenetics of the herpesviral genome / Identification and characterization of antiviral restriction factors for poxviruses

Bodo Grimbacher's picture Bodo Grimbacher
Center of Chronic Immunodeficiency, University Medical Center
Immunology and Virology

- Genetic causes of hypogammaglobulinemia (CVID) / The clinical phenotype of antibody deficiency syndromes / The genetic cause of the hyper-IgE recurrent infection syndrome (HIES) / New disease genes in severe congenital neutropenia (SCN) / The genetic cause of chronic mucocutaneous candidiasis (CMC) / The molecular pathology of chronic inflammatory bowel disease

CIBSS, EURIdoc

Georg Haecker's picture Georg Haecker
Institute of Microbiology and Hygiene
Immunology and Virology

- Molecular and Cellular Immunology

EURIdoc

Hartmut Hengel's picture Hartmut Hengel
Institute of Virology
Immunology and Virology

- Our research interest is covering virology and immunology. We focus on both cytomegalovirus-encoded and host-encoded Fc-Receptors. The former are potent manipulators of IgG and innate humoral immunity, the latter implicated in antiviral defence but also immunopathology.

EURIdoc

Philipp Henneke's picture Philipp Henneke
Center for Chronic Immunodeficiency, Center of Pediatrics and Adolescent Medicine
Immunology and Virology

- Development of cellular innate immunity against commensals of the skin (staphylococci) and respiratory/intestinal tract (streptococci) at the beginning of life in humans and mice / Receptor-based recognition of bacterial effectors, in particular lipopetides and cytolysins, by macrophages and neutrophils

CIBSS, EURIdoc

Katrin Kierdorf's picture Katrin Kierdorf
Institute of Neuropathology, University Medical Center
Immunology and Virology

- Our research group takes advantage of transgenic mice, Drosophila and cell culture systems to understand the molecular machineries guiding the development and diversity of tissue-resident macrophages and how these cells communicate throughout their network and with host tissue cells during homeostasis and disturbance.

CIBSS

Georg Kochs's picture Georg Kochs
Institute of Virology
Immunology and Virology

- Molecular biology of Orthomyxoviruses, Influenza A- and tick-transmitted Thogoto virus / Role of viral IFN antagonists for virulence in the mouse model / Antiviral function of Mx proteins / Evolution of Mx proteins in primates, rodents and bats.

Susana Minguet's picture Susana Minguet
Institute of Biology III - Molecular immunology
Immunology and Virology

- The molecular mechanisms of early T cell activation and how this knowledge can be used for treatments of human diseases / The complex interplay between the biophysical properties of the extracellular matrix and T cell infiltration to improve tumor immunotherapy / The nano-organization of the B cell antigen receptor and the mechanisms by which defective B cell activation leads to immunopathology

CIBSS

Gabriele Niedermann's picture Gabriele Niedermann
Department of Radiation Oncology, University Medical Center
Immunology and Virology

- Tumor Immunology / Tumor Immunotherapy / Radiobiology / Molecular Imaging

Wolfgang Schamel's picture Wolfgang Schamel
Institute of Biology III
Immunology and Virology

- Define the protein complexes that change in time and space within the signaling cascades of the antigen TCR

BIOSS, CIBSS, EURIdoc, SFB1381

Martin Schwemmle's picture Martin Schwemmle
Institute of Virology
Immunology and Virology

- Species transmission of highly pathogenic influenza A viruses / Emerging bat viruses / Innate immunity / Neurotropic viruses

Robert Thimme's picture Robert Thimme
Clinic for Internal Medicine II, University Medical Center
Immunology and Virology

- My research focus lies on the immune responses in hepatitis B virus (HBV) and hepatitis C virus (HCV) infection as well as hepatocellular carcinoma (HCC), specifically the immunological determinants of viral clearance and persistence.

EURIdoc

Robert Zeiser's picture Robert Zeiser
Department of Hematology and Oncology, University Medical Center
Immunology and Virology

- Tumor immunology, oncogenic signaling, allogeneic hematopoietic cell transplantation (allo-HCT), Graft-versus-host disease (GVHD), Anti-leukemia immune responses, immune checkpoint blockade therapy (ICB), immune related adverse events (irAEs).

CIBSS